Article
Cell surface markers in HTLV-1 pathogenesis.
Viruses - 1 Aug 2011
Kress Andrea K, Grassmann Ralph, Fleckenstein Bernhard
Abstract excerpt
The phenotype of HTLV-1-transformed CD4(+) T lymphocytes largely depends on defined viral effector molecules such as the viral oncoprotein Tax. In this review, we exemplify the expression pattern of characteristic lineage markers, costimulatory receptors and ligands of the tumor necrosis factor superfamily, cytokine receptors, and adhesion molecules on HTLV-1-transformed cells. These molecules may provide...
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