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Article

Not Just an Adhesion Molecule: LFA-1 Contact Tunes the T Lymphocyte Program.

Journal of immunology (Baltimore, Md. : 1950) - 15 Aug 2017

Verma Navin Kumar, Kelleher Dermot

Abstract excerpt

The αLβ2 integrin LFA-1 is known to play a key role in T lymphocyte migration, which is necessary to mount a local immune response, and is also the main driver of autoimmune diseases. This migration-triggering signaling process in T cells is tightly regulated to permit an immune response that is appropriate to the local trigger, as well as to prevent deleterious tissue-damaging bystander effects. Emerging...

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Source

Identifiers

PMID: 28784685
DOI: 10.4049/jimmunol.1700495

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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