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Article

Donor- and ligand-dependent differences in C-C chemokine receptor 5 reexpression.

Journal of virology - 1 Jan 2001

Sabbe R, Picchio G R, Pastore C, Chaloin O, Hartley O, Offord R, Mosier D E

Abstract excerpt

N-terminal modifications of the chemokine RANTES bind to C-C chemokine receptor 5 (CCR5) and block human immunodeficiency virus type 1 (HIV-1) infection with greater efficacy than native RANTES. Modified RANTES compounds induce rapid CCR5 internalization and much slower receptor reexpression than native RANTES, suggesting that receptor sequestration is one mode of anti-HIV activity. The rates of CCR5...

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Share to Blood Donors
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 11134280
DOI: 10.1128/JVI.75.2.661-671.2001
PMCID: PMC113963

Genes

CCR5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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