Article
Aggregation of RANTES is responsible for its inflammatory properties. Characterization of nonaggregating, noninflammatory RANTES mutants.
The Journal of biological chemistry - 24 Sept 1999
Appay V, Brown A, Cribbes S, Randle E, Czaplewski L G
Abstract excerpt
The biology of RANTES (regulated on activation normal T cell expressed) aggregation has been investigated using RANTES and disaggregated variants, enabling comparison of aggregated, tetrameric, and dimeric RANTES forms. Disaggregated variants retain their G(i)-type G protein-coupled receptor-medi...
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