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Article

Structural and functional studies of the potent anti-HIV chemokine variant P2-RANTES.

Proteins - 1 Feb 2010

Jin Hongjun, Kagiampakis Ioannis, Li Pingwei, Liwang Patricia J

Abstract excerpt

The N-terminal region of the chemokine RANTES is critical for its function. A synthesized N-terminally modified analog of RANTES, P2-RANTES, was discovered using a phage display selection against living CCR5-expressing cells, and has been reported to inhibit HIV-1 env-mediated cell-cell fusion at subnanomolar levels (Hartley et al. J Virol 2003;77:6637-6644). In the present study we produced this protein using E....

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Identifiers

PMID: 19722264
DOI: 10.1002/prot.22542
PMCID: PMC4306592

Genes

CCR5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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