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Article

XRCC1 and XPD genetic polymorphisms, smoking and breast cancer risk in a Finnish case-control study.

Breast cancer research : BCR - 1 Jan 2005

Metsola Katja, Kataja Vesa, Sillanpää Pia, Siivola Päivi, Heikinheimo Liisa, Eskelinen Matti, Kosma Veli-Matti, Uusitupa Matti, Hirvonen Ari

Abstract excerpt

INTRODUCTION: It has been suggested that individuals with reduced DNA repair capacities might have increased susceptibility to environmentally induced cancer. In this study, we evaluated if polymorphisms in DNA repair genes XRCC1 (Arg280His, Arg399Gln) and XPD (Lys751Gln) modify individual breast cancer risk, with emphasis on tobacco smoking. METHODS: The study population consisted of 483 incident breast cancer...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 16280050
DOI: 10.1186/bcr1333
PMCID: PMC1410770

Genes

XRCC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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