Article
Polymorphisms in DNA damage response genes and head and neck cancer risk.
Biomarkers : biochemical indicators of exposure, response, and susceptibility to chemicals - 1 Aug 2010
Flores-Obando Rafael E, Gollin Susanne M, Ragin Camille C
Abstract excerpt
BACKGROUND: Polymorphisms in DNA repair genes have been reported contributing factors in head and neck cancer risk but studies have shown conflicting results. OBJECTIVE: To clarify the impact of DNA repair gene polymorphisms in head and neck cancer risk. METHOD: A meta-analysis including 30 case-control studies was performed. RESULTS: Marginally statistically significant association was found for XRCC1 codon 399...
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