Article
Pathogenesis of non-familial colorectal carcinomas with high microsatellite instability.
Journal of clinical pathology - 1 Nov 2000
Shitoh K, Konishi F, Miyaki M, Iijima T, Furukawa T, Tsukamoto T, Nagai H
Abstract excerpt
AIMS: Microsatellite instability (MSI) was first observed in hereditary non-polyposis colorectal carcinoma (HNPCC) and was subsequently seen in non-familial colorectal carcinoma. The relation between MSI and cancer associated genes in non-familial colorectal carcinomas has yet to be evaluated. To clarify this matter, changes in cancer associated genes were examined in non-familial colorectal carcinomas. METHODS:...
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