Article
Effects of PMCA2 mutation on DPOAE amplitudes and latencies in deafwaddler mice.
Hearing research - 1 Jan 2001
Konrad-Martin D, Norton S J, Mascher K E, Tempel B L
Abstract excerpt
The deafwaddler (dfw) mouse mutant is caused by a spontaneous mutation in the gene that encodes a plasma membrane Ca(2+) ATPase (type 2), PMCA2 (Street et al., 1998. Nat. Genet. 19, 390-394), which is expressed in cochlear and vestibular hair cells. Distortion product otoacoustic emission (DPOAE) amplitudes and latencies were examined in control mice, deafwaddler mutants, and controls treated with the drug...
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