Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Maintenance of neuronal size gradient in MNTB requires sound-evoked activity.

Journal of neurophysiology - 1 Feb 2017

Weatherstone Jessica H, Kopp-Scheinpflug Conny, Pilati Nadia, Wang Yuan, Forsythe Ian D, Rubel Edwin W, Tempel Bruce L

Abstract excerpt

The medial nucleus of the trapezoid body (MNTB) is an important source of inhibition during the computation of sound location. It transmits fast and precisely timed action potentials at high frequencies; this requires an efficient calcium clearance mechanism, in which plasma membrane calcium ATPase 2 (PMCA2) is a key component. Deafwaddler (dfw2J ) mutant mice have a null mutation in PMCA2 causing deafness in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Diphtheria Toxin
Share to Evoked Potentials, Auditory

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Excitatory Amino Acid Antagonists

Share to Excitatory Postsynaptic Potentials

Share to Plasma Membrane Calcium-Transporting ATPases

Share to Presynaptic Terminals

Share to Sodium Channel Blockers

Share to Tetrodotoxin

Source

Open in PubMed Open full text

Identifiers

PMID: 27881722
DOI: 10.1152/jn.00528.2016
PMCID: PMC5304411

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Maintenance of neuronal size gradient in MNTB requires sound-evoked activity.PMID 27881722Read ↗

miR-96 is required for normal development of the auditory hindbrain.Semantic proximity Read ↗

Gating of hair cell Ca <sup>2+</sup> channels governs the activity of cochlear neuronsSemantic proximity Read ↗

The effect of progressive hearing loss on the morphology of endbulbs of Held and bushy cells.Semantic proximity Read ↗

Maturation of synaptic partners: functional phenotype and synaptic organization tuned in synchrony.Semantic proximity Read ↗

Ephrin-B reverse signaling is required for formation of strictly contralateral auditory brainstem pathways.Semantic proximity Read ↗

Protection from noise-induced hearing loss by Kv2.2 potassium currents in the central medial olivocochlear system.Semantic proximity Read ↗

Mutation of Npr2 leads to blurred tonotopic organization of central auditory circuits in mice.Semantic proximity Read ↗

Synaptic refinement of an inhibitory topographic map in the auditory brainstem requires functional Cav1.3 calcium channels.Semantic proximity Read ↗

Null mutations in EphB receptors decrease sharpness of frequency tuning in primary auditory cortex.Semantic proximity Read ↗

PMCA2 pump mutations and hereditary deafness.Semantic proximity Read ↗

Hox2 Genes Are Required for Tonotopic Map Precision and Sound Discrimination in the Mouse Auditory Brainstem.Semantic proximity Read ↗

CX3CR1 mutation alters synaptic and astrocytic protein expression, topographic gradients, and response latencies in the auditory brainstem.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.