Article
PMCA2 mutation causes structural changes in the auditory system in deafwaddler mice.
Journal of neurocytology - 1 Apr 2001
Dodson H C, Charalabapoulou M
Abstract excerpt
Homozygous deafwaddler mice (dfw/dfw) have a mutation in the gene encoding plasma membrane Ca2+ATPase isoform 2 (Pmca2). They walk with a hesitant and wobbly gait, display head bobbing and are deaf. Light microscopy and transmission electron microscopy were used to evaluate the nature and relationship of morphological changes in the cochlea, spiral ganglion cells and spherical cells of the cochlear nucleus in...
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