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Article

Auditory evoked-potential abnormalities in a mouse model of 22q11.2 Deletion Syndrome and their interactions with hearing impairment

2023-10-05

Abstract excerpt

The 22q11.2 deletion is a risk factor for multiple psychiatric disorders including schizophrenia and also increases vulnerability to middle-ear problems that can cause hearing impairment. Up to 60% of deletion carriers experience hearing impairment and ∼30% develop schizophrenia in adulthood. It is not known if these risks interact. Here we used the Df1/+ mouse model of the 22q11.2 deletion to investigate how hea...

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Literature Corpus work
e3fcb70d-da8a-5f5e-aa14-5bc5813508b9
DOI
10.1101/2023.10.04.560916
Open publication

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