Article
Molecular diversity of prostanoid receptors; subtypes and isoforms of prostaglandin E receptor.
Advances in experimental medicine and biology - 1 Jan 1997
Narumiya S
Abstract excerpt
cDNA cloning of PGE receptors revealed that there are at least three distinct subtypes of the receptor derived from different genes, which are different in ligand binding character and signal transduction. They also distribute differently in the body and localize in different cells of the organ. The cloning study also revealed that multiple isoforms of EP3 are produced by alternative splicing of its mRNA, and...
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