Association between a C+33T polymorphism in the IL-4 promoter region and total serum IgE levels.

doi:10.1046/j.1365-2222.2000.00983.x

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Article

Association between a C+33T polymorphism in the IL-4 promoter region and total serum IgE levels.

Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Dec 2000

Suzuki I, Hizawa N, Yamaguchi E, Kawakami Y

Abstract excerpt

Susceptibility to asthma and other atopic diseases is known to be associated with elevated total IgE levels. Several investigators have linked the interleukin-4 (IL-4) gene and nearby markers located on chromosome 5q to elevated total IgE levels. A single nucleotide polymorphism in the IL-4 gene...

Topics

Aged
Alleles
Asian People
Asthma
Female
Gene Frequency
Humans
Immunoglobulin E
Interleukin-4
Male
Middle Aged
Polymorphism, Genetic

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