Article
Association between a C+33T polymorphism in the IL-4 promoter region and total serum IgE levels.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology - 1 Dec 2000
Suzuki I, Hizawa N, Yamaguchi E, Kawakami Y
Abstract excerpt
Susceptibility to asthma and other atopic diseases is known to be associated with elevated total IgE levels. Several investigators have linked the interleukin-4 (IL-4) gene and nearby markers located on chromosome 5q to elevated total IgE levels. A single nucleotide polymorphism in the IL-4 gene promoter region (C+33T) has recently been identified. As part of an effort to identify genetic variants contributing to...
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