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Article

Allelic polymorphisms in the interleukin-4 promoter regions and their association with bronchial asthma among the Russian population.

International archives of allergy and immunology - 1 Jan 2006

Gervaziev Y V, Kaznacheev V A, Gervazieva V B

Abstract excerpt

BACKGROUND: Susceptibility to the development of bronchial asthma (BA) and other atopic diseases is known to be associated with genetic components. OBJECTIVE: To evaluate the possible role of the polymorphisms in IL-4 gene promoters (C-33T, C-590T and G-1098T) in modulating allergic response and asthma in the Russian population. METHODS: The polymorphism analysis was carried out by PCR-RFLP; IL-4 and total IgE...

Topics

Adolescent
Adult
Aged
Alleles
Asthma
Bronchial Hyperreactivity
Female
Genetic Predisposition to Disease
Humans
Interleukin-4
Male
Middle Aged

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Genetic

Promoter Regions, Genetic

Russia

Severity of Illness Index

Source

Identifiers

PMID: 16931887
DOI: 10.1159/000095295

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-16931887-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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