Article
Association between the polymorphisms of IL-4 gene promoter (-590C>T), IL-13 coding region (R130Q) and IL-16 gene promoter (-295T>C) and allergic asthma.
Iranian journal of allergy, asthma, and immunology - 1 Mar 2007
Hosseini-Farahabadi Sara, Tavakkol-Afshari Jalil, Rafatpanah Houshang, Farid Hosseini Reza, Khaje Daluei Mohammad
Abstract excerpt
Allergic asthma is a multifactorial disease, influenced by genetic and environmental factors. Recent family-based studies have revealed evidence for linkage of human chromosomes 5q31-33, 12q15-24, 11q13 and 15q23.6 as regions likely to contain genes related to asthma. Among the candidate genes in these regions are the genes encoding for human interleukin-4, interleukin-13 and interleukin-16. To evaluate this...
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