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Article

Counterregulatory responses to hypoglycemia in patients with glucokinase gene mutations.

Diabetes & metabolism - 1 Nov 2000

Guenat E, Seematter G, Philippe J, Temler E, Jequier E, Tappy L

Abstract excerpt

The glucokinase gene is expressed not only in pancreatic B cells and in the liver, but also in pancreatic alpha cells, and in some cells of the central nervous system. A decreased glucokinase activity in the latter cell types may interfere with counterregulatory responses to hypoglycemia. In order to assess functional consequences of glucokinase mutations, counterregulatory hormones secretion and glucose...

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PMID: 11119017

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Counterregulatory responses to hypoglycemia in patients with glucokinase gene mutations.PMID 11119017Read ↗

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Glucokinase, the pancreatic glucose sensor, is not the gut glucose sensor.Semantic proximity Read ↗

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