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Article

Recent clinical advances of glucokinase activators in the treatment of diabetes mellitus type 2.

Die Pharmazie - 1 Jun 2020

Li Wei, Zhang Xiaoqing, Sun Yan, Liu Zhaohua

Abstract excerpt

Glucokinase (GK) is an isozyme of hexokinase that catalyzes the phosphorylation of glucose. GK is present in many organs of the human body, including the liver and pancreas. GK plays an important role in promoting the synthesis of hepatic glycogen and balancing postprandial blood glucose. Mutations in the GK gene can result in the inclusion of maturity-onset diabetes of the young (MODY2) and permanent neonatal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 32539915
DOI: 10.1691/ph.2020.0409

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Recent clinical advances of glucokinase activators in the treatment of diabetes mellitus type 2.PMID 32539915Read ↗

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From clinicogenetic studies of maturity-onset diabetes of the young to unraveling complex mechanisms of glucokinase regulation.Semantic proximity Read ↗

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