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Article

Non-class II HLA gene associated with type 1 diabetes maps to the 240-kb region near HLA-B.

Diabetes - 1 Dec 2000

Nejentsev S, Gombos Z, Laine A P, Veijola R, Knip M, Simell O, Vaarala O, Akerblom H K, Ilonen J

Abstract excerpt

Several studies provide evidence that in addition to the DQ-DR genes, HLA contains another uncharacterized gene or genes associated with type 1 diabetes. Our aim was to investigate the effect of this gene independently of the DQ-DR genes and to localize it with a matched case-control study. More than 1,400 patients and 30,000 control individuals from Finland were studied. They were first genotyped for the...

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Topics

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Share to Histocompatibility Antigens Class I
Share to HLA-A Antigens

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to HLA-B Antigens

Share to HLA-DQ alpha-Chains

Share to HLA-DQ Antigens

Share to HLA-DQ beta-Chains

Share to HLA-DR Antigens

Share to HLA-DRB1 Chains

Source

Identifiers

PMID: 11118029
DOI: 10.2337/diabetes.49.12.2217

Genes

MICA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

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