Article
Microsatellite allele 5 of MHC class I chain-related gene a increases the risk for insulin-dependent diabetes mellitus in latvians.
Annals of the New York Academy of Sciences - 1 Apr 2002
Shtauvere-Brameus A, Ghaderi M, Rumba I, Sanjeevi C B
Abstract excerpt
Insulin-dependent diabetes mellitus (IDDM) is one of the most common chronic diseases. It is an autoimmune, polygenic disease, associated with several genes on different chromosomes. The most important gene is human leukocyte antigen (HLA), also known as major histocompatibility complex (MHC), which is located on chromosome 6p21.3. HLA-DQ8/DR4 and DQ2/DR3 are positively associated with IDDM and DQ6 is negatively...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
