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Article

Activated cAMP-response Element-binding Protein Regulates Neuronal Expression of Presenilin-1

1 Mar 2001

Abstract excerpt

Upon binding to the cAMP-response element of a gene's promoter, the transcription factor known as cAMP-response element-binding protein (CREB) facilitates transcription of many different neuronal genes including those involved with synaptic function. Based on our previous reports of gene structure (GenBank accession number AF029701 ), we now demonstrate that activated CREB binds to the proximal promoter of the...

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PMID: 11116137
DOI: 10.1074/jbc.m006153200

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