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CREB: A Multifaceted Target for Alzheimer’s Disease

19 Feb 2021

Abstract excerpt

Alzheimer's disease (AD) is a persistent neuropathological stipulation manifested in the form of neuronal/synapse demise, the formation of senile plaques, hyperphosphorylated tau tangles, neuroinflammation, and apoptotic cell death. The absence of a therapeutic breakthrough for AD has continued the quest to find a suitable intervention. Apart from various candidates, the cyclic AMPprotein kinase A-cAMP response...

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PMID: 33602089
DOI: 10.2174/1567205018666210218152253

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