Article
p53 expression in Wilms' tumor: a possible role as prognostic factor.
International journal of oncology - 1 Jan 2001
Beniers A J, Efferth T, Füzesi L, Granzen B, Mertens R, Jakse G
Abstract excerpt
Although a correlation between anaplasia and mutations of the p53 tumor suppressor gene has been found in Wilms' tumor (WT) a prognostic significance of p53 in WT remains largely unresolved. The goal of this study was to obtain a better understanding of the role of p53 expression in WT. Immunohistochemical analysis was performed on formalin-fixed paraffin-embedded tumor tissues from 21 patients treated in our...
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