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Article

Gene expression profiles in normal and Otx2-/- early gastrulating mouse embryos.

Proceedings of the National Academy of Sciences of the United States of America - 19 Dec 2000

Zakin L, Reversade B, Virlon B, Rusniok C, Glaser P, Elalouf J M, Brulet P

Abstract excerpt

The mouse Otx2 gene is a homeobox transcription factor required as early as gastrulation for the proper development of the head. We compared gene expression profiles in wild-type and Otx2(-/-) 6.5 days postcoitum embryos by using a serial analysis of gene expression assay adapted to microdissected structures. Among a broader list, the study of six genes found to be differentially expressed allows defining a role...

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Identifiers

PMID: 11114168
DOI: 10.1073/pnas.011513398
PMCID: PMC18928

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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