Article
Cre-mediated recombination in the pituitary gland.
Genesis (New York, N.Y. : 2000) - 1 Jan 2000
Cushman L J, Burrows H L, Seasholtz A F, Lewandoski M, Muzyczka N, Camper S A
Abstract excerpt
Organ-specific expression of a cre recombinase transgene allows for the analysis of gene function in a particular tissue or cell type. Using a 4.6 kb promoter from the mouse glycoprotein hormone alpha-subunit (alphaGSU or Cga) gene, we have generated and characterized a line of transgenic mice that express cre recombinase in the anterior and intermediate lobes of the pituitary gland. Utilizing a cre-responsive...
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