Article
Hypomorphic phenotype in mice with pituitary-specific knockout of steroidogenic factor 1.
Genesis (New York, N.Y. : 2000) - 1 Jun 2001
Zhao L, Bakke M, Krimkevich Y, Cushman L J, Parlow A F, Camper S A, Parker K L
Abstract excerpt
The bacteriophage Cre recombinase provides a powerful approach for tissue-specific gene inactivation. Using a Cre transgene driven by the common alpha subunit of glycoprotein hormones (alphaGSU-Cre), we have previously inactivated steroidogenic factor 1 (SF-1) in the anterior pituitary, causing h...
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