Article
Efficient, specific, developmentally appropriate cre-mediated recombination in anterior pituitary gonadotropes and thyrotropes.
Genesis (New York, N.Y. : 2000) - 1 Nov 2013
Pérez-Millán María Inés, Zeidler Michael G, Saunders Thomas L, Camper Sally A, Davis Shannon W
Abstract excerpt
Tissue-specific expression of cre recombinase is a well-established genetic tool to analyze gene function, and it is limited only by the efficiency and specificity of available cre mouse strains. Here, we report the generation of a transgenic line containing a cre cassette with codon usage optimized for mammalian cells (iCre) under the control of a mouse glycoprotein hormone α-subunit (αGSU) regulatory sequences...
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