Article
Development of a pituitary-specific cre line targeted to the Pit-1 lineage.
Genesis (New York, N.Y. : 2000) - 1 Jan 2008
Yin Zhirong, Williams-Simons Lisa, Rawahneh Lisa, Asa Sylvia, Kirschner Lawrence S
Abstract excerpt
Tissue-specific expression of the Cre recombinase is a well-established genetic tool to analyze gene function in specific tissues and cell types. In this report, we describe the generation of a new transgenic line that expresses Cre under the control of the rat growth hormone releasing hormone receptor (rGhrhr) promoter. This promoter, chosen to target the anterior pituitary, drives cre-mediated recombination in...
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