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Article

Role of estrogen receptor-alpha in the anterior pituitary gland.

Molecular endocrinology (Baltimore, Md.) - 1 Jun 1997

Scully K M, Gleiberman A S, Lindzey J, Lubahn D B, Korach K S, Rosenfeld M G

Abstract excerpt

Targeted insertional disruption of the mouse estrogen receptor-alpha (ER alpha) gene has provided a genetic model in which to test hypotheses that estrogens exert important effects in development and homeostatic functions of the anterior pituitary gland, particularly in the lactotroph and gonadotroph cell types. Analysis of ER alpha gene-disrupted mice reveals a marked reduction in PRL mRNA and a decrease in...

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Identifiers

PMID: 9171231
DOI: 10.1210/mend.11.6.0019

Genes

PRL

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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