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Article

Population carrier frequency of hMSH2 and hMLH1 mutations.

British journal of cancer - 1 Dec 2000

Dunlop M G, Farrington S M, Nicholl I, Aaltonen L, Petersen G, Porteous M, Carothers A

Abstract excerpt

Knowledge of population carrier frequency for DNA mismatch repair (MMR) gene mutations would contribute to understanding the burden of cancer due to genetic susceptibility, but robust prevalence estimates are lacking. To estimate carrier frequency, we genotyped a cohort of relatives of mutation carriers and determined their colorectal cancer prevalence. Systematic Finnish and US data were combined with Scottish...

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Identifiers

PMID: 11104559
DOI: 10.1054/bjoc.2000.1520
PMCID: PMC2363440

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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