Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Penetrance of colorectal cancer among MLH1/MSH2 carriers participating in the colorectal cancer familial registry in Ontario

23 Aug 2009

Abstract excerpt

BACKGROUND: Several DNA mismatch repair (MMR) genes, responsible for the majority of Lynch Syndrome cancers, have been identified, predominantly MLH1 and MSH2, but the risk associated with these mutations is still not well established. The aim of this study is to provide population-based estimates of the risks of colorectal cancer (CRC) by gender and mutation type from the Ontario population. METHODS: We analyzed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Colorectal Cancer Screening and Detection
Share to Genetic factors in colorectal cancer
Share to Multiple and Secondary Primary Cancers

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 19698169
DOI: 10.1186/1897-4287-7-14

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Penetrance of colorectal cancer among MLH1/MSH2 carriers participating in the colorectal cancer familial registry in OntarioPMID 19698169Read ↗

Calculation of risk of colorectal and endometrial cancer among patients with Lynch syndrome.Semantic proximity Read ↗

Cancer risks associated with germline mutations in MLH1, MSH2, and MSH6 genes in Lynch syndrome.Semantic proximity Read ↗

Cancer Risks for PMS2-Associated Lynch Syndrome.Semantic proximity Read ↗

Cancer-risk by family history and mismatch-repair mutation in Lynch syndrome.Semantic proximity Read ↗

Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study.Semantic proximity Read ↗

Cancer Risks for<i>MLH</i><i>1</i>and<i>MSH</i><i>2</i>Mutation CarriersSemantic proximity Read ↗

Mutation spectrum and risk of colorectal cancer in African American families with Lynch syndrome.Semantic proximity Read ↗

Genotype-phenotype comparison of German MLH1 and MSH2 mutation carriers clinically affected with Lynch syndrome: a report by the German HNPCC Consortium.Semantic proximity Read ↗

Cancer risks by gene, age, and gender in 6350 carriers of pathogenic mismatch repair variants: findings from the Prospective Lynch Syndrome DatabaseSemantic proximity Read ↗

Colorectal and other cancer risks for carriers and noncarriers from families with a DNA mismatch repair gene mutation: a prospective cohort study.Semantic proximity Read ↗

Risks of Lynch Syndrome Cancers for MSH6 Mutation CarriersSemantic proximity Read ↗

Cancer risks for<i>MSH6</i>pathogenic variant carriersSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.