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Article

A directed mutagenesis screen in Drosophila melanogaster reveals new mutants that influence hedgehog signaling.

Genetics - 1 Dec 2000

Haines N, van den Heuvel M

Abstract excerpt

The Hedgehog signaling pathway has been recognized as essential for patterning processes in development of metazoan animal species. The signaling pathway is, however, not entirely understood. To start to address this problem, we set out to isolate new mutations that influence Hedgehog signaling. We performed a mutagenesis screen for mutations that dominantly suppress Hedgehog overexpression phenotypes in the...

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Identifiers

PMID: 11102373
DOI: 10.1093/genetics/156.4.1777
PMCID: PMC1461372

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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