Article
Notch and Wingless modulate the response of cells to Hedgehog signalling in the Drosophila wing.
Developmental biology - 1 Aug 2002
Glise Bruno, Jones D Leanne, Ingham Philip W
Abstract excerpt
During Drosophila wing development, Hedgehog (Hh) signalling is required to pattern the imaginal disc epithelium along the anterior-posterior (AP) axis. The Notch (N) and Wingless (Wg) signalling pathways organise the dorsal-ventral (DV) axis, including patterning along the presumptive wing margin. Here, we describe a functional hierarchy of these signalling pathways that highlights the importance of competing...
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