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Article

A gain-of-function suppressor screen for genes involved in dorsal-ventral boundary formation in the Drosophila wing.

Genetics - 1 Jan 2008

Bejarano Fernando, Luque Carlos M, Herranz Héctor, Sorrosal Georgina, Rafel Neus, Pham Thu Thuy, Milán Marco

Abstract excerpt

The Drosophila wing primordium is subdivided into a dorsal (D) and a ventral (V) compartment by the activity of the LIM-homeodomain protein Apterous in D cells. Cell interactions between D and V cells induce the activation of Notch at the DV boundary. Notch is required for the maintenance of the compartment boundary and the growth of the wing primordium. Beadex, a gain-of-function allele of dLMO, results in...

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Identifiers

PMID: 18202376
DOI: 10.1534/genetics.107.081869
PMCID: PMC2206080

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Source receipt: pubmed, retrieved 7 Sept 2026.

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A gain-of-function suppressor screen for genes involved in dorsal-ventral boundary formation in the Drosophila wing.PMID 18202376Read ↗

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