Article
Clonal analysis of Hedgehog signaling in Drosophila somatic tissues.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2007
Bankers Christine M, Hooper Joan E
Abstract excerpt
To fully understand how animals develop, it is often necessary to remove the function of a particular gene in a specific cell type or subset of cells. In Drosophila melanogaster, mosaic animals have been widely utilized to study cell fate, growth and patterning, and restriction of cell fate. This chapter describes using FLP recombinase to generate mosaic Drosophila, discussing the chromosomes and cross scheme,...
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