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Article

Generation of tension by skinned fibers and intact skeletal muscles from desmin-deficient mice.

Biochemical and biophysical research communications - 19 Nov 2000

Wieneke S, Stehle R, Li Z, Jockusch H

Abstract excerpt

We have investigated the physiological role of desmin in skeletal muscle by measuring isometric tension generated in skinned fibres and intact skeletal muscles from desmin knock-out (DES-KO) mice. About 80% of skinned single extensor digitorum longus (EDL) fibres from adult DES-KO mice generated tensions close to that of wild-type (WT) controls. Weights and maximum tensions of intact EDL but not of soleus (SOL)...

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Source

Identifiers

PMID: 11097852
DOI: 10.1006/bbrc.2000.3810

Genes

DES

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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