Article
Desmin is a modifier of dystrophic muscle features in Mdx mice
2019-08-23
Abstract excerpt
Duchenne muscular dystrophy (DMD) is a severe neuromuscular disease, caused by dystrophin deficiency. Desmin is like dystrophin associated to costameric structures bridging sarcomeres to extracellular matrix that are involved in force transmission and skeletal muscle integrity. In the present study, we wanted to gain further insight into the roles of desmin which expression is increased in the muscle from the mous...
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Identifiers and source
- Literature Corpus work
- 42873032-602f-5054-afc3-4f1207006153
- DOI
- 10.1101/742858
