Article
Full flexibility genotyping of single nucleotide polymorphisms by the GOOD assay.
Nucleic acids research - 1 Dec 2000
Sauer S, Lechner D, Berlin K, Plançon C, Heuermann A, Lehrach H, Gut I G
Abstract excerpt
Recently a facile method for genotyping single nucleotide polymorphisms (SNPs) using MALDI mass spectrometry, termed the GOOD assay, was developed. It does not require any purification and is performed with simple liquid handling, thermal incubation and cycling steps. Although this method is well suited to automation and high-throughput analysis of SNPs, it did not allow full flexibility due to lack of certain...
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