Article
Facile method for automated genotyping of single nucleotide polymorphisms by mass spectrometry.
Nucleic acids research - 1 Mar 2002
Sauer Sascha, Gelfand David H, Boussicault Francis, Bauer Keith, Reichert Fred, Gut Ivo G
Abstract excerpt
In the future, analysis of single nucleotide polymorphisms (SNPs) should become a powerful tool for many genetic applications in areas such as association studies, pharmacogenetics and traceability in the agro-alimentary sector. A number of technologies have been developed for high-throughput genotyping of SNPs. Here we present the simplified GOOD assay for SNP genotyping by matrix-assisted laser...
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