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Article

Single-nucleotide polymorphisms: analysis by mass spectrometry.

Nature protocols - 1 Jan 2006

Sauer Sascha, Reinhardt Richard, Lehrach Hans, Gut Ivo G

Abstract excerpt

Matrix-assisted laser desorption-ionization (MALDI) mass spectrometry has evolved as a powerful method for analyzing nucleic acids. Here we provide protocols for genotyping single-nucleotide polymorphisms (SNPs) by MALDI based on PCR and primer extension to generate allele-specific products. Furt...

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Identifiers

PMID: 17487158
DOI: 10.1038/nprot.2006.257

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17487158-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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