Article
A novel procedure for efficient genotyping of single nucleotide polymorphisms.
Nucleic acids research - 1 Mar 2000
Sauer S, Lechner D, Berlin K, Lehrach H, Escary J L, Fox N, Gut I G
Abstract excerpt
Due to the surge in interest in using single nucleotide polymorphisms (SNPs) for genotyping a facile and affordable method for this is an absolute necessity. Here we introduce a procedure that combines an easily automatable single tube sample preparation with an efficient high throughput mass spectrometric analysis technique. Known point mutations or single nucleotide polymorphisms are easily analysed by this...
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