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Article

Beta-arrestin 2: a receptor-regulated MAPK scaffold for the activation of JNK3.

Science (New York, N.Y.) - 24 Nov 2000

McDonald P H, Chow C W, Miller W E, Laporte S A, Field M E, Lin F T, Davis R J, Lefkowitz R J

Abstract excerpt

beta-Arrestins, originally discovered in the context of heterotrimeric guanine nucleotide binding protein-coupled receptor (GPCR) desensitization, also function in internalization and signaling of these receptors. We identified c-Jun amino-terminal kinase 3 (JNK3) as a binding partner of beta-arr...

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Identifiers

PMID: 11090355
DOI: 10.1126/science.290.5496.1574

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-11090355-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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