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Article

"Gene-swap knock-in" cassette in mice to study allelic differences in human genes.

Annals of the New York Academy of Sciences - 1 Jan 2000

Nebert D W, Dalton T P, Stuart G W, Carvan M J

Abstract excerpt

Genetic differences in environmental toxicity and cancer susceptibility among individuals in a human population often reflect polymorphisms in the genes encoding drug-metabolizing enzymes (DMEs), drug transporters, and receptors that control DME levels. This field of study is called "ecogenetics", and a subset of this field--concerning genetic variability in response to drugs--is termed "pharmacogenetics"....

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PMID: 11083106
DOI: 10.1111/j.1749-6632.2000.tb06876.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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