Article
The utilization of quantitative trait loci in toxicogenetics.
Journal of experimental animal science - 1 Sept 1993
McClearn G E, Jones B, Blizard D A, Plomin R
Abstract excerpt
With the increasing number of marker loci available in mouse, the traditional method of recombinant inbred strains can be extended to searches for quantitative trait loci (QTL) influencing continuously distributed phenotypes. These loci have effect sizes too small to be easily detectable by conventional single-locus techniques. Collective, several QTL may account for a substantial proportion of the phenotypic...
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