Article
Contribution of HLA class II genes to end stage renal disease in mexican patients with type 2 diabetes mellitus.
Human immunology - 1 Oct 2000
Pérez-Luque E, Malacara J M, Olivo-Díaz A, Aláez C, Debaz H, Vázquez-Garcia M, Garay M E, Nava L E, Burguete A, Gorodezky C
Abstract excerpt
To analyze the contribution of MHC class II genes in type 2 diabetes mellitus (DM) with end stage renal disease (ESRD), we examined the distribution of HLA-DRB1, DQA1, DQB1 loci in Mexican Mestizos of Central Mexico, using PCR-SSOP and PCR-SSP. Three groups were included: 47 type 2 diabetic ESRD patients; 42 patients with ESRD and 50 type 2 DM patients with no kidney complication. The results were compared with...
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