HLA-DRB1*14 is associated with lower odds of symptomatic SARS-CoV-2 infection in Mexican individuals.

doi:10.3389/fimmu.2026.1907153

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Article

HLA-DRB1*14 is associated with lower odds of symptomatic SARS-CoV-2 infection in Mexican individuals.

Frontiers in immunology - 1 Jan 2026

Hernández Eric G, Daza-Mendoza Diego A, González-Rivas Enrique, Serrano-Vázquez Angélica, Pérez-Juárez Horacio, Uribe-García Alina, Rostro-Alonso Gareth O, Morán-Silva Patricia, Rojas-Velázquez Liliana, Ximénez García Cecilia

Abstract excerpt

Mexico has been one of the countries most affected by the COVID-19 pandemic. Several factors can influence the susceptibility to SARS-CoV-2 infection, particularly highly polymorphic genes in the HLA system. Therefore, this pilot study analyzed the association between HLA-DRB1 genetic polymorphisms and the susceptibility and/or resistance to symptomatic SARS-CoV-2 infection in a population from the Metropolitan...

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Topics

Humans
HLA-DRB1 Chains
Mexico
COVID-19
Female
Male

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

SARS-CoV-2

Genetic Predisposition to Disease

Adult

Middle Aged

Gene Frequency

Alleles

Polymorphism, Genetic

Pilot Projects

Aged

Source

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Identifiers

PMID: 42745975
DOI: 10.3389/fimmu.2026.1907153
PMCID: PMC13574783

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