Article
Genomic footprinting of the yeast zinc finger protein Rme1p and its roles in repression of the meiotic activator IME1.
Nucleic acids research - 15 May 1998
Shimizu M, Li W, Covitz P A, Hara M, Shindo H, Mitchell A P
Abstract excerpt
The zinc finger protein Rme1p is a negative regulator of the meiotic activator IME1 in Saccharomyces cerevisiae . Prior studies have shown that Rme1p binds in vitro to a site near nt -2030 in the IME1 upstream region, but a genomic mutation in that site has little effect on repression of IME1 . T...
Topics
- Binding Sites
- DNA Footprinting
- DNA, Fungal
- Fungal Proteins
- Gene Expression Regulation, Fungal
- Mediator Complex
- Meiosis
- Mutation
- Nuclear Proteins
- RNA, Fungal
- RNA, Messenger
- Recombinant Fusion Proteins
- Repressor Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins
- Trans-Activators
- Transcription Factors
- Zinc Fingers