Article
Global role for chromatin remodeling enzymes in mitotic gene expression.
Cell - 1 Sept 2000
Krebs J E, Fry C J, Samuels M L, Peterson C L
Abstract excerpt
Regulation of eukaryotic gene expression requires ATP-dependent chromatin remodeling enzymes, such as SWI/SNF, and histone acetyltransferases, such as Gcn5p. Here we show that SWI/SNF remodeling controls recruitment of Gcn5p HAT activity to many genes in late mitosis and that these chromatin remodeling enzymes play a role in regulating mitotic exit. In contrast, interphase expression of GAL1, HIS3, PHO5, and PHO8...
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