Article
The utility of Ki-ras mutation analysis in the cytologic diagnosis of pancreatobiliary neoplasma.
Cancer journal (Sudbury, Mass.) - 1 Jan 2000
Dillon D A, Johnson C C, Topazian M D, Tallini G, Rimm D L, Costa J C
Abstract excerpt
PURPOSE: Mutations involved in neoplastic progression may be able to serve as markers for the presence of small numbers of neoplastic cells that would otherwise escape detection in diagnostic assays. Previous retrospective studies have suggested that the sensitivity of the cytologic diagnosis of pancreatic and biliary tract carcinomas is improved when analysis includes Ki-ras exon 1, which is commonly mutated in...
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