Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Detection of c-K-ras mutations in fine needle aspirates from human pancreatic adenocarcinomas.

Cancer research - 15 Feb 1990

Shibata D, Almoguera C, Forrester K, Dunitz J, Martin S E, Cosgrove M M, Perucho M, Arnheim N

Abstract excerpt

Formalin-fixed paraffin-embedded tissue specimens obtained by fine needle aspiration of pancreatic masses from 47 patients were examined retrospectively for cytology and the presence of mutant c-K-ras oncogenes. Point mutations of c-K-ras in codon 12 were detected by RNA-DNA RNAse A mismatch cleavage after in vitro DNA amplification of the cellular c-K-ras sequences by the polymerase chain reaction. Of the 36...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Biopsy, Needle
Share to Codon

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genes, ras

Share to Mutation

Share to Pancreatic Neoplasms

Share to Polymerase Chain Reaction

Share to RNA, Messenger

Source

Identifiers

PMID: 2404591

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Detection of c-K-ras mutations in fine needle aspirates from human pancreatic adenocarcinomas.PMID 2404591Read ↗

Diagnostic utility of K-ras mutations in fine-needle aspirates of pancreatic masses.Semantic proximity Read ↗

Detection of c-Ki-ras mutation by PCR/RFLP analysis and diagnosis of pancreatic adenocarcinomas.Semantic proximity Read ↗

Analysis of K-ras oncogene mutation directly applied to atypical cell clusters on cytologic smear slides of bile and pancreatic juice.Semantic proximity Read ↗

K-ras gene mutation in the diagnosis of ultrasound guided fine-needle biopsy of pancreatic masses.Semantic proximity Read ↗

Clinical usefulness of K-ras gene mutation detection and cytology in pancreatic juice in the diagnosis and screening of pancreatic cancerSemantic proximity Read ↗

Kras mutation analysis of fine needle aspirate under EUS guidance facilitates risk stratification of patients with pancreatic mass.Semantic proximity Read ↗

K-ras mutations in DNA extracted from the plasma of patients with pancreatic carcinoma: diagnostic utility and prognostic significance.Semantic proximity Read ↗

K-ras gene mutations in the diagnosis of fine-needle aspirates of pancreatic masses: prospective study using two techniques with different detection limits.Semantic proximity Read ↗

K-ras mutations in the duodenal fluid of patients with pancreatic carcinoma.Semantic proximity Read ↗

DNA mutational differences in cytological specimens from pancreatic cancer and cholangiocarcinoma.Semantic proximity Read ↗

Detection of K-ras gene mutation by liquid biopsy in patients with pancreatic cancer.Semantic proximity Read ↗

K-ras oncogene mutations indicate malignancy in cystic tumors of the pancreas.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.